Cindy McCain, the wife of 2008 Republican presidential nominee Senator John McCain, is to appear in a play about Proposition 8, the US state of California’s controversial ban on same-sex marriage.

Mrs McCain is set to star in the Dustin Lance Black show at the Phoenix Herberger Theater Center’s production of the play, along with her daugher Meghan.

The Senator’s wife will play one of the plaintiffs in the Prop 8 case, and appearing alongside her will be the wife of Phoenix Mayor, Greg Stanton, Nicole.

The production is set to undertake a national tour, and several stars have been noted as taking part, including  Brad Pitt, George Clooney, Martin Sheen and Jamie Lee Curtis.

The play, 8, focuses on the historic Hollingsworth v Perry trial, and its historic closing arguments in the summer of 2010.

In 2008, Mrs McCain appeared in a NOH8 avert, as part of the pro-equality campaign.

Meghan McCain, said earlier this month that “being a Republican who supports gay marriage is a bitch,” shortly following an announcement from her father who refused to back down on his anti-gay marriage stance, and has previously compared same-sex families to abortions.

The US Supreme Court recently heard arguments around Proposition 8, the state of California’s ban on equal marriage. During the hearing, the justices questioned the meaning of marriage, and challenged arguments for the ban. 

One day prior, the Supreme Court Justices indicated a possible interest in striking down the Defense of Marriage Act (DOMA), as it heard arguments around the issue.

A decision by the Supreme Court is expected in both cases by the end of June.